Assistant Professor
- B.Sc. (Western University)
- Ph.D. (York University)
Office: LHS D220
Phone: 705-748-1011 ext. 6463
Email: stephanietobin@trentu.ca
Twitter: @stephcellsci
Stephanie Tobin's Google Scholar
Research Interests
- Stem cell physiology
- Striated muscle pathologies
- Aging
- Inflammation and tissue repair
- Signal transduction
My research interests can be summarized into three pillars: aging, striated muscle inflammation/repair and stem cell fate. More specifically, I am interested in how bone marrow stem cell aging influences striated muscle inflammation and repair. To do this I use transcriptomics, in vitro models of myogenesis, macrophage differentiation and mesenchymal stem cell culture, and in vivo models of skeletal and cardiac muscle injury.
Teaching
To be determined
Professional Experience
Postdoctoral Fellow, Toronto General Hospital Research Institute (TGHRI), University Health Network (UHN)
Selected Publications
Tobin, S.W., Alibhai, F.J., Wlodarek, L., Yeganeh, A., Millar, S., Wu, J., Weisel, R.D., and Li, R.K. Delineating the relationship between immune system aging and muscle stem cell function in muscle repair. Aging Cell. 20(2):e13312. (2021)
Tobin, S.W., Alibhai, F.J., Weisel, R.W. and Li, R.K. Considering cause and effect of immune cell aging on cardiac repair after myocardial infarction. Cells. 9(8):E1894. (2020).
Tobin, S.W., Hashemi, S., Dadson, K., Ebrahimian, K., Turdi, S., Zhao, J., Sweeney, G., Grigull, J., and McDermott, J.C. Heart Failure and MEF2 Transcriptome Dynamics in Response to β-Blockers. Sci Rep. 7(1):4476. (2017)
Tobin, S.W., Li, S., Li, J., Wu, J. Yeganeh, A., Yu, P., Weisel, R.D., and Li, R.K. Dual roles for bone marrow-derived Sca-1 cells in cardiac function. FASEB J. 31(7):2905-2915. (2017).
