Craig Brunetti
The study of viral immune modulation strategies has increased our understanding of the diverse array of mechanisms that viruses use to circumvent the host immune response as well as providing a greater understanding of host immune function. In particular, the large DNA viruses, such as the Herpesviridae and Poxviridae families encode an array of viral proteins that subvert immune system function at many different levels. Although many immune evasion genes have been identified, the cellular targets of these virulence factors are often specific to a particular virus or viral famil