Course Listings

Essential aspects of general, molecular, and intermolecular chemistry. Topics include atomic structure, bonding, equilibrium, acids-bases, gases, liquids, solutions, and the solid state. Emphasis is on the relation between molecular and physical properties. Prerequisite: 4U Chemistry or equivalent or permission of instructor (see notes).

Essential aspects of physical, inorganic, organic and biological chemistry. Topics include redox chemistry, kinetics, thermodynamics and an introduction to inorganic, environmental, organic and biological chemistry. Prerequisite: CHEM 1000H or equivalent or permission of instructor (see notes).

An introduction and overview of organic compounds and reactions within synthetic methodology will be presented for alkanes, alkenes, alkynes and alkyl halides. The concepts of stereochemistry are introduced. The driving force behind reactions is examined. Prerequisite: CHEM 1000H and 1010H.

The thermodynamics and kinetics pertaining to mechanistic organic chemistry are investigated with case example classes of compounds. The application and theory of MS, IR, UV, and NMR spectroscopy in the structural determination of organic compounds are introduced. Prerequisite: CHEM 2100H.

The bonding and structure of coordination compounds of the d-block transition metals; mechanisms of ligand exchange and redox reactions; physical and chemical properties of d-block elements. Prerequisite: CHEM 2500H.

Introduces key molecules and concepts in biochemistry. Topics include the properties of water, the thermodynamics of biological systems, and the behaviour of biomolecules in water. Focuses on each of the four major classes of biomolecules-proteins, nucleic acids, carbohydrates, and lipids-as they apply to biological systems. Prerequisite: CHEM 1000H and 1010H.

Cross-listed: BIOL-2300H

The theory and practice of chemical analysis including dealing with chemical data, wet chemical techniques, electrochemistry, instrumental methods, and separations. Prerequisite: CHEM 1000H and 1010H.

An introduction to the properties of atoms and molecules, and the theory and practice of chemical reaction kinetics. Prerequisite: Both CHEM 1000H and 1010H and either MATH 1120H (or 1100Y or 1101Y) or 1005H with permission of instructor.

Exposes the main chemical principles that govern environmental processes in natural waters such as rivers, lakes, estuaries, and oceans. Includes the chemical composition of aquatic systems and the behaviour of aqueous pollutants such as metals and pesticides. Prerequisite: CHEM 1000H and 1010H. Recommended: CHEM-ERSC 2610H. Excludes CHEMERSC 2600Y.

Cross-listed: ERSC-2620H

Course Description: Introduction to tools for analysis and design of chemical processes. This will include flow of energy and materials through various processes and production of energy and mass balances as well as vapour-liquid equilibria. A major component of this course will be a team-based design project of a manufacturing process.

The structure, reactivity, and synthesis of biologically and industrially important organic molecules are considered. Particular emphasis is placed upon oxygen, sulfur, and nitrogen organic functional group chemistry. The thermodynamics and kinetics of reaction mechanisms of these functional groups are considered. Prerequisite: CHEM 2100H and 2110H. Excludes CHEM 3100Y.

The structure, reactivity, and synthesis of biologically important organic molecules are considered. Particular emphasis is placed upon the chemistry of carbohydrates, amino acids, peptides, proteins, lipids, and nucleic acids. An introduction to the organic chemistry of metabolic pathways, including pericyclic reactions, is provided. Prerequisite: CHEM 3102H. Excludes CHEM 3100Y.

Theory and application of molecular mechanics, semi-empirical and ab initio methods in the investigation of molecular structure, properties, and reactivity. Prerequisite: CHEM 2500H, 2100H, and 2110H. Excludes CHEM 4120H.

Structure and bonding in compounds of the main group elements, including symmetry, correlation of physical and chemical properties with electronic structure, crystalline solids, and band theory. Qualitative comparison of the second-row elements with the heavier elements in the group. Prerequisite: CHEM 2200H and 2500H.

The structure and function or proteins, key protein biophysical methods, and enzyme mechanisms are treated in detail. Students use web-based resources such as ExPASy and the Protein Data Bank, and gain practical laboratory experience in bioseparations and the determination of enzyme rate parameters. Prerequisite: CHEM-BIOL 2300H, and one of CHEM 2100H or 2110H.

Cross-listed: BIOL-3310H

The key topics are biological processes that produce and use high-energy biomolecules. These include membrane transport, multienzyme pathways, and their regulation. With their skills acquired in CHEM-BIOL 3310H, students are given more freedom for independent laboratory work in devising and executing their own enzyme purification scheme. Prerequisite: CHEM-BIOL 3310H. Excludes CHEM-BIOL 3300H.

Cross-listed: BIOL-3320H

Theory and practice of chromatography, sampling, and quality control. Particular emphasis is placed on applications in environmental analysis. Prerequisite: CHEM 2400H.

Cross-listed: ERSC-3400H, FRSC-3400H

Modern analytical spectroscopic instrumentation, techniques, and application to the analysis of organic, inorganic, and biochemical contaminants with a particular focus on the forensic and environmental fields are addressed. Prerequisite: CHEM 2400H. Strongly recommended: CHEM 2100H and 2110H.

Cross-listed: ERSC-3410H, FRSC-3410H

An introduction to thermodynamics: the First and Second Laws. The properties of gases, thermochemistry, and principles of chemical equilibrium. Phase diagrams of typical materials. Prerequisite: Both CHEM 1000H and 1010H and either MATH 1120H (or 1100Y or 1101Y) or 1005H with permission of instructor. Excludes CHEM 2510H.

Focuses on the parameters controlling the natural water chemistry in surface and subsurface systems. These key processes involve chemical reactions and kinetics, pH control of equilibria, chemical speciation and photochemical processes. Combines theory and environmental applications. Prerequisite: CHEM-ERSC 2620H (or 2600Y); and either CHEM 2400H or both ERSC 2220H and 2230H. Recommended: CHEM-ERSC 3600H.

Cross-listed: ERSC-3610H

This course focuses on the instrumental analytical and materials analysis of sample types routinely analyzed within the Chemistry section of Ontario's Centre for Forensic Sciences. Specifically, students discuss the analysis of ignitable liquid residues and explosive materials, gunshot residue, textiles, and glass. Prerequisite: CHEM 2400H and one of FRSC 2220H or CHEM 2110H.

Cross-listed: FRSC-3720H

Study, usually involving experimental research, under the supervision of a faculty member; includes two seminars and a written thesis. At least eight hours per week. Pre- or co-requisites: Two Chemistry lecture half-courses at the 4000 level; an average of 75% in all previous Chemistry courses; and permission of instructor. Contact coordinator as soon as possible and no later than the end of the preceding Winter term.

Study, usually involving experimental research, under the supervision of a faculty member; includes two seminars and a written thesis. At least eight hours per week. Pre- or co-requisites: Two Chemistry lecture half-courses at the 4000 level; an average of 75% in all previous Chemistry courses; and permission of instructor. Contact coordinator as soon as possible and no later than the end of the preceding Winter term.

Study, usually involving experimental research, under the supervision of a faculty member; includes two seminars and a written thesis. At least eight hours per week. Pre- or co-requisites: Two Chemistry lecture half-courses at the 4000 level; an average of 75% in all previous Chemistry courses; and permission of instructor. Contact coordinator as soon as possible and no later than the end of the preceding Winter term.

Approximately 16 hours per week; otherwise, as CHEM 4010Y. Pre- or co-requisites: Two Chemistry lecture half-courses at the 4000 level; an average of 75% in all previous Chemistry courses; and permission of instructor.

Study, usually involving experimental research, under the supervision of a faculty member; includes two seminars and a written thesis. At least eight hours per week. Pre- or co-requisites: Two CHEM or BIOL lecture half-courses at the 4000 level; an average of 75% in all previous Chemistry courses; and permission of the instructor. Contact coordinator as soon as possible and no later than the end of the previous Winter term. Only available to students who are pursuing the Biochemistry & Molecular Biology degree and may not be combined with more than 1.0 credit in a project course in any other dicipline.

Study, usually involving experimental research, under the supervision of a faculty member; includes two seminars and a written thesis. At least eight hours per week. Pre- or co-requisites: Two CHEM or BIOL lecture half-courses at the 4000 level; an average of 75% in all previous Chemistry courses; and permission of the instructor. Contact coordinator as soon as possible and no later than the end of the previous Winter term. Only available to students who are pursuing the Biochemistry & Molecular Biology degree and may not be combined with more than 1.0 credit in a project course in any other dicipline.

At least 16 hours per week; otherwise as CHEM 4030Y. May not be combined with any other project courses for credit toward the Biochemistry & Molecular Biology degree. Prerequisite: An average of 75% in all previous Chemistry courses and permission of instructor.

Cross-listed: BIOL-4040D

Medicinal and pharmaceutical chemistry are highly interdisciplinary areas of practical and applied chemistry that are adjoined with chemical and structural biology and flank areas such as biochemistry, molecular biology, pharmacology, toxicology, and veterinary and human medicine. This course presents the design, synthesis, and analysis of pharmaceutical and bio-active molecules. Prerequisite: CHEM 3102H and 3110H (or 3100Y).

Polymers are one of the most far-reaching chemical developments in everyday life. This course explores the chemistry of polymer materials including their synthesis, characterization, and applications, with a focus on the major classes of polymers and recent advances in polymer materials. Prerequisite: CHEM 2100H and 2110H.

Introduces synthetic organic chemical processes and products that are benign by design. Concepts of ACS 12 principles of green chemistry and the ISO life-cycle analysis metrics are introduced to assess sustainability of chemical processes and products. Prerequisite: CHEM 2110H and 2500H

Structure and bonding theory in inorganic molecules is expanded for extended structures (clusters and solids). Topics include band structures in metals, semiconductors, and insulators; superconductors and nanoscale materials. Prerequisite: CHEM 3200H or both CHEM 2200H and 4200H.

The essential biological roles of metals are usually acknowledged but seldom discussed in most biochemistry courses. Includes an introduction to coordination chemistry and a survey of the roles of metals in enzyme catalysis, oxygen transport, photosynthesis, cell mobility, gene expression, and environmental toxicity. Prerequisite: CHEM-BIOL 3310H and 3320H (3300H); or CHEM 2200H and CHEM-BIOL 2300H.

Cross-listed: BIOL-4300H

A survey of the questions that are of greatest interest to biochemists. Relies extensively on reading and understanding primary literature sources published within the last four years. Students give presentations in class as part of the course evaluation. Prerequisite: CHEM-BIOL 3310H and 3320H (3300H).

Cross-listed: BIOL-4310H

An introduction to the principles and modern applications of mass spectrometry in chemical analysis. Topics include fundamentals of ion chemistry, ionization techniques, mass-analyzer and detector design, and applications of hybrid and tandem instrumental design in analytical and organic chemistry and biochemistry. Prerequisite: CHEM 2500H.

Focuses on the practical employment of NMR within organic, biochemical, and environmental fields. Provides a review of the basic theory and instrumentation of NMR, introduces simple 1D, followed by more complex 2D and 3D spectral acquisition and interpretation techniques, and includes heteronuclear elements. Prerequisite: CHEM 2100H, 2110H, and 2500H. Highly recommended: CHEM 3410H. Excludes CHEM 4130H.

Introduction to theory and practice of photochemistry. Topics include interaction of matter with light, unimolecular decomposition, energy transfer processes, photochemical activation, and organic photochemistry, as well as applications in environmental and industrial processes. Prerequisite: CHEM 2500H.

Modern chemical thermodynamics and kinetics. Introduction to statistical thermodynamics: molecular interpretation of entropy and internal energy. Reaction rate theories: gas phase and solution reaction dynamics. Prerequisite: Both CHEM 2500H and 3520H (2510H), and MATH 1120H (or 1100Y or 1101Y); or permission of instructor. Recommended: MATH 2110H and 2120H. Excludes CHEM 3510H.

Designed for students whose main background is in chemistry, this course is an expanded study of the unique properties and role of water in nature and technology. Topics include essential properties of water and aqueous mixtures, chemistry behind clean drinking water, municipal wastewater treatment, water chemistry in power generation systems. Prerequisite: One of CHEM 2500H or 3520H (2510H) or both CHEM-ERSC 2610H and 2620H (or 2600Y).

Provides a chemical perspective of molecules related to death and poisoning. A wide range of both natural and synthetic classes are explored with respect to their synthesis/extraction, toxicology, use within chemical poisonings and chemical warfare, and their analytical detection and quantification. Prerequisite: CHEM 2300H and one of 3400H or 3410H.

Cross-listed: FRSC-4710H

Topics from one of the following fields: analytical chemistry, biochemistry, inorganic chemistry, organic chemistry, physical chemistry and theoretical chemistry. Project work outside the laboratory may be involved. Offered only by prior arrangement through department office.

Topics from one of the following fields: analytical chemistry, biochemistry, inorganic chemistry, organic chemistry, physical chemistry and theoretical chemistry. Project work outside the laboratory may be involved. Offered only by prior arrangement through department office.

Topics from one of the following fields: analytical chemistry, biochemistry, inorganic chemistry, organic chemistry, physical chemistry and theoretical chemistry. Project work outside the laboratory may be involved. Offered only by prior arrangement through department office.